Cerecor Appoints H. Jeffery Wilkins MD as Chief Development Officer

3/6/20

H. Jeffery Wilkins

ROCKVILLE, Md., March 06, 2020 (GLOBE NEWSWIRE) -- Cerecor Inc. (NASDAQ: CERC), a biopharmaceutical company focused on becoming a leader in development and commercialization of treatments for rare pediatric and orphan diseases, today announced that Jeff Wilkins, MD has joined the Company as its Chief Development Officer, with a specific focus on CERC-002, CERC-006 and CERC-007 clinical development programs.

"We are delighted to welcome Dr. Wilkins to the organization," said Mike Cola, Chief Executive Officer. "With his experience in discovery, leading new product development programs and bringing products to market, Dr. Wilkins is a key addition for the Company. We believe he will provide valuable patient insights and clinical guidance as we continue to progress our programs in auto-immune/ inflammatory diseases and complex lymphatic malformations."

Dr. Wilkins brings over 19 years of clinical research experience to the Company, most recently serving as Chief Medical Officer of Zyla Life Sciences. Previously, he held position of Chief Medical Officer at Onspira Therapeutics, Lycera, and Ceptaris Therapeutics, Inc., where he led clinical programs from IND Phase I trials to regulatory approval (including Valchlor®). Prior to this, Dr. Wilkins was Vice President, Worldwide Clinical Research, Inflammation/Oncology at Cephalon Inc., where he led clinical development, medical affairs and business development efforts in both therapy areas. Previously, he was Senior Vice President of Clinical Development with Ception Therapeutics, where he headed a successful program in eosinophilic asthma prior to the company’s acquisition by Cephalon. Dr. Wilkins entered the pharmaceutical industry with GlaxoSmithKline, where he rose to become Vice President of Discovery Medicine for GSK’s Center of Excellence in External Drug Discovery. He also served as Group Director of GSK’s urology franchise, responsible for Levitra® and the launch of VESIcare®. Earlier in his career as a practicing primary care physician, Dr. Wilkins was Co-Founder and Chief Executive Officer of TriValley Primary Care, a large multi-center primary care group in Southeastern Pennsylvania.

Dr. Wilkins received his M.D. from Temple University School of Medicine and his B.S. from Bucknell University.

"I am excited for the opportunity to be part of the Cerecor management team and to lead the development programs across three of our clinical assets," said Dr. Wilkins. “I look forward to applying my program management and clinical development skills to guide the development of CERC-002 in Pediatric-onset Crohn’s Disease, CERC-006 for complex Lymphatic Malformations and CERC-007 for Adult Onset Still’s Disease (AOSD) and Multiple Myeloma (MM)."

About CERC-002

CERC-002 (formerly AEVI-002) is an anti-LIGHT (Lymphotoxin-like, exhibits Inducible expression, and competes with HSV Glycoprotein D for HVEM, a receptor expressed by Tlymphocytes (part of the Tumor Necrosis Super Family 14)), fully human, monoclonal antibody being developed as a treatment for Pediatric Crohn’s Disease.

About CERC-006

CERC-006 (formerly AEVI-006) is a dual mTOR inhibitor (a class of drugs that inhibit the mammalian target of rapamycin) being developed as a treatment for complex Lymphatic Malformations (LM). LM patients often have activating mutations along the PI3K/AKT/mTOR pathway; sirolimus, an mTORC1 inhibitor, has demonstrated clinical utility in LM. CERC-006 has the potential to improve upon both the safety and efficacy of mTOR inhibition in LM.

About CERC-007

CERC-007 (formerly AEVI-007) is a fully human, anti-IL-18 monoclonal antibody with the potential to address multiple auto-inflammatory diseases, including Adult Onset Stills Disease (AOSD) and Multiple Myeloma (MM). IL-18 is a pro-inflammatory cytokine that stimulates the production of interferon gamma; patients with ASOD and MM show elevated serum levels of IL-18.

About Cerecor

Cerecor is a biopharmaceutical company focused on becoming a leader in development and commercialization of treatments for rare pediatric and orphan diseases. The Company is advancing an emerging clinical-stage pipeline of innovative therapies. The Company’s pediatric rare disease pipeline is led by CERC-801, CERC-802 and CERC-803 (“CERC-800 programs”), which are therapies for inborn errors of metabolism, specifically disorders known as Congenital Disorders of Glycosylation (”CDGs”). The FDA granted Rare Pediatric Disease Designation and Orphan Drug Designation (“ODD”) to all three CERC-800 programs, thus potentially qualifying the Company to receive a Priority Review Voucher (“PRV”) upon approval of a new drug application (“NDA”). The Company is also developing CERC-002, CERC-006 and CERC-007. CERC-007 is an anti-IL-18 monoclonal antibody being developed for autoimmune inflammatory diseases such as Adult Onset Stills Disease (AOSD) and Multiple Myeloma. CERC-006 is a dual mTOR inhibitor targeted towards complex Lymphatic Malformations, also with initial proof-of-concept in patients expected in 2021. CERC-002 is an anti-LIGHT monoclonal antibody currently in a Phase 1 clinical trial.

For more information about Cerecor, please visit www.cerecor.com.

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